Paclitaxel protein-bound is a cancer (antineoplastic) medication. Paclitaxel protein-bound
interferes with the growth of cancer cells and slows their growth and spread in the body.
Paclitaxel protein-bound is used in the treatment breast cancer.
Paclitaxel protein-bound may also be used for purposes other than those listed in this
medication guide.
Paclitaxel protein-bound should only be administered under the supervision of a qualified
healthcare provider experienced in the use of cancer chemotherapeutic agents.
Your doctor will determine the correct amount and frequency of treatment with paclitaxel
protein-bound depending upon the type of cancer being treated and other factors. Talk to your doctor
if you have any questions or concerns regarding the treatment schedule.
Your doctor will probably want you to have regularly scheduled blood tests and other medical
evaluations during treatment with paclitaxel protein-bound to monitor progress and side effects.
Skin accidentally exposed to paclitaxel protein-bound should be rinsed thoroughly with soap
and warm water.
Your healthcare provider will store paclitaxel protein-bound as directed by the manufacturer. If
you are storing paclitaxel protein-bound at home, follow the directions provided by your healthcare
provider.
If you experience any of the following serious side effects from paclitaxel protein-bound, seek
emergency medical attention or contact your doctor immediately:
an allergic reaction (including difficulty breathing; closing of the
throat; swelling of the lips, tongue, or face; or hives);
decreased bone marrow function and blood problems
(extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs
of infection);
liver damage (abdominal pain, yellowing of the skin or
eyes); or
severe nausea, vomiting, or diarrhea;
numbness or tingling; or
irregular heartbeats.
Other, less serious side effects may be more likely to occur. Continue taking
paclitaxel protein-bound and talk to your doctor if you experience:
tissue or vein reactions near the site of administration;
low red blood cell count;
joint or muscle pain;
sores in the mouth;
hair loss; or
mild to moderate nausea, vomiting, diarrhea, or loss of
appetite.
Other side effects have also been reported. Discuss with your doctor any
side effect that occurs during treatment with paclitaxel protein-bound.
Do not receive "live” vaccines during treatment with paclitaxel protein-bound.
Administration of a live vaccine may be dangerous during treatment with paclitaxel protein-bound.
Paclitaxel protein-bound can interact with many other medications, including other
chemotherapy drugs. Talk to your doctor and pharmacist before taking any other prescription or
over-the-counter medicines, including herbal products, during treatment with paclitaxel protein-bound.
Do not receive "live” vaccines during treatment with paclitaxel protein-bound.
Administration of a live vaccine may be dangerous during treatment with paclitaxel protein-bound.
Skin accidentally exposed to paclitaxel protein-bound should be rinsed thoroughly with soap
and warm water.
If for any reason an overdose of paclitaxel protein-bound is suspected, seek emergency
medical attention or contact your healthcare provider immediately.
Symptoms of a paclitaxel protein-bound overdose tend to be similar to side effects caused by
the medication, although often more severe.
Paclitaxel protein-bound should only be administered under the supervision of a qualified
healthcare provider experienced in the use of cancer chemotherapeutic agents.
Serious side effects have been reported with the use of paclitaxel protein-bound including:
allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or
hives); decreased bone marrow function and blood problems (extreme fatigue; easy bruising or
bleeding; black, bloody or tarry stools; fever or chills; or signs of infection); numbness or tingling;
irregular heartbeats; and others. Talk to your doctor about the possible side effects from treatment with
paclitaxel protein-bound.
Do not take paclitaxel protein-bound without first talking to your doctor if you have
kidney disease;
liver disease;
heart disease; or
poor bone marrow function.
The use of paclitaxel protein-bound may be dangerous if you have any of the
conditions listed above.
Men should not father a child while receiving treatment with paclitaxel protein-bound.
Paclitaxel protein-bound is in the FDA pregnancy category D. This means that paclitaxel
protein-bound is known to be harmful to an unborn baby. Do not use paclitaxel
protein-bound without first talking to your doctor if you are pregnant. Discuss with your doctor the
appropriate use of birth control during treatment with paclitaxel protein-bound if either you or your
partner is of childbearing potential.
It is not known whether paclitaxel protein-bound passes into breast milk. Do not take
paclitaxel protein-bound without first talking to your doctor if you are breast feeding a baby.
Paclitaxel protein-bound is available with a prescription under the brand names Abraxane.
Other brand or generic formulations may also be available. Ask your healthcare provider or pharmacist
any questions you have about this medication, especially if it is new to you.
Remember, keep this and all other medicines out of the reach of children, never share your
medicines with others, and use this medication only for the indication prescribed.
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