Atropine, hyoscyamine, and scopolamine decrease the amount of nasal and respiratory
secretions (release of fluids) in the body that may cause sneezing, runny nose, and postnasal drip.
Chlorpheniramine is an antihistamine. It works in your body against a natural chemical
called histamine. Chlorpheniramine prevents sneezing; itchy, watery eyes and nose; and other
symptoms of allergies and hay fever.
Phenylephrine is a decongestant. It works by shrinking blood vessels in the body,
reducing blood flow and allowing nasal passages to open up.
Atropine, chlorpheniramine, hyoscyamine, phenylephrine, and scopolamine is used to
treat symptoms of allergies, hay fever, and the common cold.
This medication may also be used for purposes other than those listed here.
Take this medication exactly as it was prescribed for you. Do not take it in larger doses or
for longer than recommended by your doctor. An overdose of this medication can cause serious
harm.
Take each dose with a full glass of water.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is
specially made to release medicine slowly in the body. Breaking the pill would cause too much
of the drug to be released at one time.
If your symptoms do not improve, if they get worse, or if you have a fever, talk to your
doctor.
Store this medication at room temperature away from moisture and heat.
Get emergency medical help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Other, less serious side effects may be more likely to occur. Continue taking this
medication and talk to your doctor if you have any of these less serious side effects:
dryness of the eyes, nose, and mouth;
blurred vision; or
difficulty urinating.
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially bothersome.
Do not take this medication together with the following drugs:
a monoamine oxidase inhibitor (MAOI) taken in the past 14 days,
including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Carbex), or
tranylcypromine (Parnate);
medicines that make you sleepy (such as alcohol, cold
medicine, pain medication, muscle relaxants, and medicine for seizures, depression, or anxiety);
or
other medications that also contain atropine,
chlorpheniramine, hyoscyamine, phenylephrine, or scopolamine.
Check the labels of all other medications you take.
There may be other drugs not listed that can affect atropine, chlorpheniramine,
hyoscyamine, phenylephrine, and scopolamine. Tell your doctor about all the prescription and
over-the-counter medications you use. This includes vitamins, minerals, herbal products, and
drugs prescribed by other doctors. Do not start using a new medication without telling your
doctor.
Avoid becoming overheated in hot weather. Atropine and hyoscyamine increase the risk
of heat stroke because they cause decreased sweating.
Do not take atropine, chlorpheniramine, hyoscyamine, phenylephrine, and
scopolamine if you have taken selegiline (Eldepryl, Carbex) or a monoamine oxidase inhibitor
(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in
the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Avoid drinking alcohol because it may increase drowsiness and dizziness while
taking atropine, chlorpheniramine, hyoscyamine, phenylephrine, and scopolamine.
Avoid using other drugs that make you sleepy (such as cold medicine, pain medication,
muscle relaxants, and medicine for seizures, depression, or anxiety). Other medications may also
contain atropine, chlorpheniramine, hyoscyamine, phenylephrine, scopolamine or other similar
drugs. You may accidentally take too much of these medicines and dangerous sedation could
result.
This medication can cause side effects that may impair your thinking or reactions.
Be careful if you drive or do anything that requires you to be awake and alert.
Seek emergency medical attention if you think you have used too much of this
medicine. Symptoms of an atropine, chlorpheniramine, hyoscyamine, phenylephrine, and
scopolamine overdose may include a dry mouth, large pupils, flushing, seizures, nausea, and
vomiting.
Take the missed dose as soon as you remember. If it is almost time for your next dose,
skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
This medication can cause side effects that may impair your thinking or reactions.
Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol because it may increase drowsiness and dizziness while
taking atropine, chlorpheniramine, hyoscyamine, phenylephrine, and scopolamine.
Avoid using other drugs that make you sleepy (such as cold medicine, pain medication,
muscle relaxants, and medicine for seizures, depression, or anxiety). Other medications may also
contain atropine, chlorpheniramine, hyoscyamine, phenylephrine, scopolamine or other similar
drugs. You may accidentally take too much of these medicines and dangerous sedation could
result.
Do not take atropine, chlorpheniramine, hyoscyamine, phenylephrine, and
scopolamine if you have taken selegiline (Eldepryl, Carbex) or a monoamine oxidase inhibitor
(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in
the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
If your symptoms do not improve, if they get worse, or if you have a fever, talk to your
doctor.
Before taking this medication, tell your doctor if you have:
epilepsy or another seizure disorder;
peripheral vascular disease such as Raynaud’s syndrome;
thyroid problems;
asthma, emphysema, or chronic obstructive pulmonary
disease (COPD);
diabetes;
glaucoma;
an ulcer or an obstruction in the stomach;
bladder problems or difficulty urinating;
an enlarged prostate;
high blood pressure, irregular heartbeats, or any type of
heart disease;
kidney problems; or
liver problems.
If you have any of the conditions listed above, you may not be able to
take this medication, or you may require a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant during treatment.
This medication can pass into breast milk and may be harmful to a nursing baby. Do
not take this medication without telling your doctor if you are breast-feeding a baby.
If you are over 60 years of age, you may be more likely to have side effects from this
medication. Your doctor may prescribe a lower dose.
Consult your doctor before giving this medication to a child. Children are more
sensitive to the effects of medicines and may have unusual reactions.
Your pharmacist has additional information about atropine, chlorpheniramine,
hyoscyamine, phenylephrine, and scopolamine written for health professionals that you may read.
Atropine, chlorpheniramine, hyoscyamine, phenylephrine, and scopolamine is available
both with a prescription under the brand name AccuHist LA. Other brand or generic formulations
may also be available. Ask your pharmacist any questions you have about this medication,
especially if it is new to you.
Remember, keep this and all other medicines out of the reach of children, never share
your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate,
up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive.
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that uses outside of the United States are appropriate. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
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to serve end-users viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare
practitioners. Healthcare practitioners should use their professional judgment in using the information provided. The absence of a warning for a
given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for
any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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