Take acetaminophen and butalbital exactly as directed by your doctor. If you do not understand
these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Take acetaminophen and butalbital with food or milk if it upsets your stomach.
Never take more acetaminophen and butalbital than is prescribed for you. If your pain is
not being adequately treated, talk to your doctor.
Do not share this medication with anyone else.
Store this medication at room temperature away from heat, moisture, and the reach of
children.
If you experience any of the following serious side effects, stop taking acetaminophen and
butalbital and seek emergency medical attention:
an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives);
liver damage (yellowing of the skin or eyes, nausea,
abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
blood problems (easy or unusual bleeding or bruising).
These side effects are very rare and are not likely to occur during proper
treatment with acetaminophen and butalbital.
Other, less serious side effects may be more likely to occur. Continue to take acetaminophen
and butalbital and talk to your doctor if you experience
dry mouth;
nausea, vomiting, abdominal pain, or decreased appetite;
dizziness, tiredness, or lightheadedness;
drowsiness;
confusion;
agitation, irritability, or excitability;
rash or itching;
feeling of intoxication;
shortness of breath;
nervousness or anxiety; or
headache.
Butalbital may be habit forming.
Side effects other than those listed here may also occur. Talk to your doctor about any side
effect that seems unusual or that is especially bothersome.
Do not take acetaminophen and butalbital if you have taken a monoamine oxidase inhibitor
(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last
14 days. Dangerous side effects could result.
Acetaminophen and butalbital may increase the effects of other drugs that cause drowsiness,
including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain
relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are
taking, and do not take any medicine unless your doctor approves.
Many other medicines contain acetaminophen, especially over-the-counter pain, fever, cold,
and allergy medications. Too much acetaminophen can be very dangerous.
Drugs other than those listed here may also interact with acetaminophen and butalbital. Talk to
your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Use caution when driving, operating machinery, or performing other hazardous activities.
Butalbital may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these
activities.
Avoid sleeping pills, antihistamines, sedatives, and tranquilizers except under the supervision of
your doctor. These may also make you drowsy.
Avoid alcohol. Alcohol taken during therapy with acetaminophen and butalbital can be very
damaging to your liver and can increase drowsiness and dizziness.
Check the acetaminophen content of other over-the-counter and prescription products while
taking this medication. You should not exceed 4 grams (4000 mg) of acetaminophen per day.
Symptoms of an acetaminophen and butalbital overdose include nausea, vomiting, diarrhea,
abdominal pain, sweating, seizures, drowsiness, decreased breathing, dizziness or fainting, confusion, an
irregular heartbeat, and coma.
Take the missed dose as soon as you remember. Do not take a double dose
of this medication. Wait the prescribed amount of time before taking your next dose.
If you are taking acetaminophen and butalbital on an as-needed basis, missing a dose is not
usually a problem. Take the missed dose as soon as you remember and do not take another dose for
the amount of time prescribed.
Use caution when driving, operating machinery, or performing other hazardous activities.
Butalbital will cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these
activities.
Avoid sleeping pills, antihistamines, sedatives, and tranquilizers except under the supervision of
your doctor. These may also make you drowsy.
Avoid alcohol. Alcohol taken during therapy with acetaminophen and butalbital can be very
damaging to your liver and can increase drowsiness and dizziness.
Check the acetaminophen content of other over-the-counter and prescription products while
taking this medication. You should not exceed 4 grams (4000 mg) of acetaminophen per day.
Never take more acetaminophen and butalbital than is prescribed for you. If your pain is
not being adequately treated, talk to your doctor.
This medication is habit forming and should only be used under close supervision. Take this
drug only for as long as it is prescribed , in the amounts it is prescribed, and no more frequently than
prescribed.
Do not take acetaminophen and butalbital without first talking to your doctor if you drink
more than three alcoholic beverages per day or if you have had alcoholic liver disease. You may not be
able to take acetaminophen and butalbital, or you may require a lower dose.
Do not take acetaminophen and butalbital if you have porphyria.
Before taking this medication, tell your doctor if you have
kidney disease, or
liver disease.
You may not be able to take acetaminophen and butalbital, or you may
require a lower dose or special monitoring during treatment if you have any of the conditions listed
above.
Acetaminophen and butalbital is in the FDA pregnancy category C. This means that it is not
known whether this combination will harm an unborn baby. Do not take this medication without first
talking to your doctor if you are pregnant.
Acetaminophen and butalbital both pass into breast milk and may harm a baby. Do not take
this medication without first talking to your doctor if you are breast-feeding a baby.
Acetaminophen and butalbital has not been approved for use in children younger than 12 years
of age.
Acetaminophen and butalbital is available with a prescription under several brand and generic
names. Ask your pharmacist any questions you have about this medication especially if it is new to you.
Remember, keep this and all other medicines out of the reach of children, never share your
medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate,
up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive.
Multum information has been compiled for use by healthcare practitioners and end-users in the United States. Cerner Multum does not warrant
that uses outside of the United States are appropriate. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or
to serve end-users viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare
practitioners. Healthcare practitioners should use their professional judgment in using the information provided. The absence of a warning for a
given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for
any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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