Take acetaminophen and tramadol exactly as it was prescribed for you. Do not take it in
larger doses or for longer than recommended by your doctor. Follow the directions on your
prescription label.
Do not take more of this medication than is recommended. An
acetaminophen and tramadol overdose can be fatal. The maximum amount of
acetaminophen and tramadol is 2 tablets per dose, or 8 tablets per day.
Take this medicine with a full glass of water.
Acetaminophen and tramadol can be taken with or without food, but take it the same way
each time.
Do not stop using this medication suddenly without talking to your doctor. You may
need to gradually reduce the dose. Withdrawal symptoms such as anxiety, sweating, nausea,
diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems may occur when
you stop using acetaminophen and tramadol.
Call your doctor at once if you have any of these withdrawal symptoms after you stop
using acetaminophen and tramadol.
Store acetaminophen and tramadol at room temperature away from moisture and
heat.
Get emergency medical help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using acetaminophen and tramadol and call your doctor at once if you have any
of these serious side effects:
seizure (convulsions);
a red, blistering, peeling skin rash; or
shallow breathing, weak pulse.
Continue taking acetaminophen and tramadol and talk to your doctor if
you have any of these less serious side effects:
dizziness, drowsiness, weakness;
nausea, vomiting, constipation, loss of appetite;
blurred vision;
flushing (redness, warmth, or tingly feeling); or
sleep problems (insomnia).
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially bothersome.
Before taking acetaminophen and tramadol, tell your doctor if you also use:
carbamazepine (Tegretol);
warfarin (Coumadin);
digoxin (Lanoxin, Lanoxicaps);
ketoconazole (Nizoral);
erythromycin (E-Mycin, E.E.S., Ery-Tab);
rifampin (Rifadin, Rimactane, Rifater);
St. John’s wort;
quinidine (Quinaglute, Quinadex, Cardioquin, Quinora); or
an antidepressant such as amitriptyline (Elavil), citalopram
(Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro),
fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline
(Pamelor); paroxetine (Paxil), or sertraline (Zoloft).
If you are using any of these drugs, you may not be able to use
acetaminophen and tramadol or you may need dosage adjustments or special tests during
treatment.
There may be other drugs not listed that can affect acetaminophen and tramadol. Tell
your doctor about all the prescription and over-the-counter medications you use. This includes
vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a
new medication without telling your doctor.
Do not drink alcohol while you are taking acetaminophen and tramadol. Alcohol may
cause a dangerous decrease in your breathing when used together with acetaminophen and
tramadol.
Avoid using drugs that make you sleepy (such as cold medicine, other pain medications,
muscle relaxants, and medicine for seizures, depression or anxiety). These drugs may slow your
breathing or increase drowsiness when used together with acetaminophen and tramadol.
Acetaminophen and tramadol can cause side effects that may impair your thinking or
reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Do not use any other over-the-counter cough, cold, allergy, or pain medication
without first asking your doctor or pharmacist. Acetaminophen is contained in many cold and
pain medicines available over the counter. If you take certain products together you may
accidentally take too much acetaminophen. Read the label of any other medicine you are using
to see if it contains acetaminophen.
Seek emergency medical attention if you think you have used too much of this
medicine. A acetaminophen and tramadol overdose can be fatal.
Symptoms of a acetaminophen and tramadol overdose may include drowsiness, shallow
breathing, slow heartbeat, extreme weakness, cold or clammy skin, stomach pain, loss of
appetite, dark urine, jaundice (yellowing of the skin or eyes, feeling light-headed, fainting, or
coma.
Take the missed dose as soon as you remember. If it is almost time for your next dose,
skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Do not take more of this medication than is recommended. An
acetaminophen and tramadol overdose can be fatal. The maximum amount of
acetaminophen and tramadol is 2 tablets per dose, or 8 tablets per day.
Do not use any other over-the-counter cough, cold, allergy, or pain medication
without first asking your doctor or pharmacist. Acetaminophen is contained in many cold and
pain medicines available over the counter. If you take certain products together you may
accidentally take too much acetaminophen. Read the label of any other medicine you are using
to see if it contains acetaminophen.
Tell your doctor if you drink more than three alcoholic beverages per day or if you have
ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains
acetaminophen.
Seizures (convulsions) have occurred in some people taking acetaminophen and tramadol.
You may be more likely to have a seizure while taking acetaminophen and tramadol if you have a
history of seizures or head injury, a metabolic disorder, a brain or spinal cord infection, or if you
are taking certain medicines. Talk with your doctor about your individual risk of having a
seizure from this medicine.
While you are taking acetaminophen and tramadol, do not drink alcohol or use drugs
that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and
medicine for seizures, depression or anxiety). These drugs may slow your breathing or increase
drowsiness when used together with acetaminophen and tramadol.
Acetaminophen and tramadol can cause side effects that may impair your thinking or
reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Do not take this medication if you are allergic to acetaminophen and tramadol, if you
are intoxicated (drunk), or if you have recently used any of the following drugs:
alcohol;
narcotic pain medicine;
sedatives or tranquilizers (such as Valium);
medicine for depression or anxiety;
medicine for mental illness (such as bipolar disorder,
schizophrenia); or
street drugs.
Tell your doctor if you drink more than three alcoholic beverages per
day or if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take
medication that contains acetaminophen.
Seizures have occurred in some people taking acetaminophen and tramadol. Your risk of
a seizure may be higher if you have any of these conditions:
a history of drug or alcohol addiction;
a history of epilepsy or other seizure disorder;
a history of head injury;
a metabolic disorder;
an infection of your brain or spinal cord, such as meningitis
or encephalitis;
if you are also taking an antidepressant, mood stabilizer, or
another narcotic pain medicine; or
if you have taken an MAO inhibitor such as isocarboxazid
(Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or
tranylcypromine (Parnate) within the past 14 days.
Talk with your doctor about your individual risk of having a seizure
from this medicine.
Before taking acetaminophen and tramadol, tell your doctor if you are allergic to any
drugs, or if you have:
kidney disease;
liver disease;
asthma or other breathing disorder;
a stomach disorder; or
a history of depression, mental illness, or suicide attempt.
If you have any of these conditions, you may not be able to use
acetaminophen and tramadol, or you may need a dosage adjustment or special tests during
treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby.
Acetaminophen and tramadol may also cause serious or fatal side effects in a newborn if the
mother uses the medication during pregnancy or labor. Tell your doctor if you are pregnant or
plan to become pregnant during treatment.
Acetaminophen and tramadol can pass into breast milk and may harm a nursing baby.
Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not give this medicine to a child younger than 16 years of age.
Acetaminophen and acetaminophen and tramadol is available with a prescription under
the brand name Ultracet. Other brand or generic formulations may also be available. Ask your
pharmacist any questions you have about this medication, especially if it is new to you.
Remember, keep this and all other medicines out of the reach of children, never share
your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate,
up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive.
Multum information has been compiled for use by healthcare practitioners and end-users in the United States. Cerner Multum does not warrant
that uses outside of the United States are appropriate. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or
to serve end-users viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare
practitioners. Healthcare practitioners should use their professional judgment in using the information provided. The absence of a warning for a
given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for
any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2007 Cerner Multum, Inc. All rights reserved.
Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement,
which can be accessed by clicking on this link.
